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InnateDB Protein
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IDBP-627614.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Card10
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Protein Name
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caspase recruitment domain family, member 10
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Synonyms
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AI449026; Bimp1; Carma3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000131003
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InnateDB Gene
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IDBG-159820 (Card10)
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Protein Structure
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| Function |
Activates NF-kappa-B via BCL10 and IKK.
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
Highly expressed in kidney, heart followed by brain, lung, liver, skeletal muscle and testis.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
9
[view]
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| Protein-Protein |
9
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
4 [view]
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Molecular Function |
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| Biological Process |
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GO:0007250
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activation of NF-kappaB-inducing kinase activity
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GO:0042981
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regulation of apoptotic process
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| Cellular Component |
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| PDB ID |
MGI:2146012
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| InterPro |
IPR001315
CARD domain
IPR011029
Death-like domain
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| PFAM |
PF00619
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| PRINTS |
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| PIRSF |
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| SMART |
SM00114
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| TIGRFAMs |
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| Modification |
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| SwissProt |
P58660
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| PhosphoSite |
PhosphoSite-P58660
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
105844
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| UniGene |
Mm.17629
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Card10
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AF363456
BC060203
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| GenPept |
AAH60203
AAK60136
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Version 5.4