Version 5.4
Mus musculus Protein: Aif1
Summary
InnateDB Protein IDBP-628138.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aif1
Protein Name allograft inflammatory factor 1
Synonyms AI607846; AIF-1; D17H6S50E; G1; Iba1;
Species Mus musculus
Ensembl Protein ENSMUSP00000134107
InnateDB Gene IDBG-177226 (Aif1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0051017 actin filament bundle assembly
Cellular Component
GO:0001726 ruffle
GO:0001891 phagocytic cup
GO:0005737 cytoplasm
GO:0005884 actin filament
Protein Structure and Domains
PDB ID MGI:1343098
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UYJ2
UniProt Splice Variant
Entrez Gene 11629
UniGene Mm.10747
RefSeq
MGI ID
MGI Symbol Aif1
OMIM
CCDS
HPRD
IMGT
EMBL CR974444
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca