Version 5.4
Mus musculus Protein: Trpm8
Summary
InnateDB Protein IDBP-628147.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trpm8
Protein Name transient receptor potential cation channel, subfamily M, member 8
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000131209
InnateDB Gene IDBG-179466 (Trpm8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0009266 response to temperature stimulus
GO:0009409 response to cold
GO:0034220 ion transmembrane transport
GO:0050955 thermoception
GO:0051289 protein homotetramerization
GO:0055085 transmembrane transport
GO:0070207 protein homotrimerization
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID MGI:2181435
InterPro IPR005821 Ion transport domain
PFAM PF00520
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R4D5
PhosphoSite PhosphoSite-Q8R4D5
TrEMBL
UniProt Splice Variant
Entrez Gene 171382
UniGene Mm.218753
RefSeq XP_006529290
MGI ID
MGI Symbol Trpm8
OMIM
CCDS CCDS48316
HPRD
IMGT
EMBL AC087780 AC102505 AF481480 AY095352 BC117934 CH466520
GenPept AAI17935 AAL79553 AAM23261 EDL40112

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca