InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Flot1

Summary

InnateDB Protein

IDBP-628282.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Flot1

Protein Name

flotillin 1

Synonyms

reggie-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000134699

InnateDB Gene

IDBG-179083 (Flot1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	73 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0035255	ionotropic glutamate receptor binding

Biological Process

GO:0007409	axonogenesis
GO:0035023	regulation of Rho protein signal transduction
GO:0072659	protein localization to plasma membrane

Cellular Component

GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0005886	plasma membrane
GO:0005901	caveola
GO:0008180	COP9 signalosome
GO:0016020	membrane
GO:0016600	flotillin complex
GO:0034451	centriolar satellite
GO:0042383	sarcolemma
GO:0045121	membrane raft

Protein Structure and Domains

PDB ID

MGI:1100500

InterPro

IPR001107 Band 7 protein

PFAM

PF01145

PRINTS

PIRSF

SMART

SM00244

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3XA73

UniProt Splice Variant

Entrez Gene

14251

UniGene

Mm.2931

RefSeq

MGI ID

MGI Symbol

Flot1

OMIM

CCDS

HPRD

IMGT

EMBL

CR974451

GenPept