InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Creb1

Summary

InnateDB Protein

IDBP-628303.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Creb1

Protein Name

cAMP responsive element binding protein 1

Synonyms

2310001E10Rik; 3526402H21Rik; AV083133; Creb; Creb-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000132860

InnateDB Gene

IDBG-161359 (Creb1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 181 interaction(s) predicted by orthology.

Experimentally validated
Total	36 [view]
Protein-Protein	22 [view]
Protein-DNA	14 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	181 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006468	protein phosphorylation
GO:0007409	axonogenesis
GO:0007595	lactation
GO:0007613	memory
GO:0008361	regulation of cell size
GO:0010033	response to organic substance
GO:0021983	pituitary gland development
GO:0030879	mammary gland development
GO:0033363	secretory granule organization
GO:0040018	positive regulation of multicellular organism growth
GO:0042493	response to drug
GO:0045087	innate immune response (InnateDB)
GO:0045672	positive regulation of osteoclast differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046887	positive regulation of hormone secretion
GO:0060428	lung epithelium development
GO:0060430	lung saccule development
GO:0060509	Type I pneumocyte differentiation
GO:0071294	cellular response to zinc ion

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

MGI:88494

InterPro

IPR001630 cAMP response element binding (CREB) protein
IPR003102 Coactivator CBP, pKID
IPR004827 Basic-leucine zipper domain
IPR008917 Transcription factor, Skn-1-like, DNA-binding domain

PFAM

PF02173
PF00170
PF07716

PRINTS

PR00041

PIRSF

SMART

SM00338

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt