Version 5.4
Homo sapiens Protein: CSHL1
Summary
InnateDB Protein IDBP-64183.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSHL1
Protein Name chorionic somatomammotropin hormone-like 1
Synonyms CS-5; CSHP1; CSL; hCS-L;
Species Homo sapiens
Ensembl Protein ENSP00000309524
InnateDB Gene IDBG-64181 (CSHL1)
Protein Structure
UniProt Annotation
Function May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation. {ECO:0000269PubMed:8083227}.
Subcellular Localization Secreted {ECO:0000269PubMed:8083227}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001400 Somatotropin hormone
IPR009079 Four-helical cytokine-like, core
PFAM PF00103
PRINTS PR00836
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14406
PhosphoSite PhosphoSite-
TrEMBL I6L999
UniProt Splice Variant
Entrez Gene 1444
UniGene
RefSeq NP_072103
HUGO HGNC:2442
OMIM 603515
CCDS CCDS11652
HPRD 04623
IMGT
EMBL AC127029 BC029365 BC119747 CH471109 J03071
GenPept AAA52550 AAH29365 AAI19748 EAW94245 EAW94246 EAW94253 EAW94262 EAW94264

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca