Homo sapiens Protein: FHL2
Summary
InnateDB Protein IDBP-64517.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FHL2
Protein Name four and a half LIM domains 2
Synonyms AAG11; DRAL; FHL-2; SLIM-3; SLIM3;
Species Homo sapiens
Ensembl Protein ENSP00000344266
InnateDB Gene IDBG-64511 (FHL2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 115 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 115 [view]
Protein-Protein 113 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0050681 androgen receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0009725 response to hormone
GO:0030521 androgen receptor signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
PFAM PF00412
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6I9R8
UniProt Splice Variant
Entrez Gene 2274
UniGene
RefSeq XP_005263959
HUGO HGNC:3703
OMIM 602633
CCDS
HPRD 04026
IMGT
EMBL AB038794 AC012360 AC068273 AC108058 AK313841 BC012742 BC014397 BC093049 BT006960 CH471127 CR457437 DQ307067 L42176 U29332 U60117
GenPept AAA85333 AAC50794 AAC52073 AAH12742 AAH14397 AAH93049 AAP35606 AAY14896 AAY15012 ABC25549 BAA92253 BAG36573 CAG33718 EAX01758 EAX01759 EAX01760