InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLDN11

Summary

InnateDB Protein

IDBP-64551.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLDN11

Protein Name

claudin 11

Synonyms

OSP; OTM;

Species

Homo sapiens

Ensembl Protein

ENSP00000064724

InnateDB Gene

IDBG-64549 (CLDN11)

Protein Structure

UniProt Annotation

Function

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.

Subcellular Localization

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007283	spermatogenesis
GO:0008366	axon ensheathment
GO:0016338	calcium-independent cell-cell adhesion

Cellular Component

GO:0005886	plasma membrane
GO:0005923	tight junction
GO:0016021	integral component of membrane
GO:0045178	basal part of cell
GO:0070062	extracellular vesicular exosome