Version 5.4
Homo sapiens Protein: KLK15
Summary
InnateDB Protein IDBP-64925.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLK15
Protein Name kallikrein-related peptidase 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000314783
InnateDB Gene IDBG-64923 (KLK15)
Protein Structure
UniProt Annotation
Function Protease whose physiological substrate is not yet known.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Highest expression in the thyroid gland. Also expressed in the prostate, salivary, and adrenal glands and in the colon testis and kidney. {ECO:0000269PubMed:11010966}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q9H2R5
TrEMBL S5TEP0
UniProt Splice Variant
Entrez Gene 55554
UniGene Hs.567535
RefSeq NP_001264010
HUGO HGNC:20453
OMIM 610601
CCDS CCDS62766
HPRD 07490
IMGT
EMBL AC010325 AC011523 KF053148
GenPept AGS43805

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca