Version 5.4
Homo sapiens Protein: DEFB104A
Summary
InnateDB Protein IDBP-6644.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEFB104A
Protein Name defensin, beta 104A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000320813
InnateDB Gene IDBG-6642 (DEFB104A)
Protein Structure
UniProt Annotation
Function Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. {ECO:0000269PubMed:11481241}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested. {ECO:0000269PubMed:11481241}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WTQ1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 503618
UniGene Hs.742246
RefSeq NP_525128
HUGO HGNC:18115
OMIM
CCDS CCDS34834
HPRD 10870
IMGT
EMBL AJ314834 AJ314835 BC100848 BC100849 BC100850 BC100851
GenPept AAI00849 AAI00850 AAI00851 AAI00852 CAC85511 CAC85520

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca