InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AKAP4

Summary

InnateDB Protein

IDBP-66998.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AKAP4

Protein Name

A kinase (PRKA) anchor protein 4

Synonyms

AKAP 82; AKAP-4; AKAP82; CT99; FSC1; hAKAP82; HI; p82; PRKA4;

Species

Homo sapiens

Ensembl Protein

ENSP00000365232

InnateDB Gene

IDBG-66994 (AKAP4)

Protein Structure

UniProt Annotation

Function

Major structural component of sperm fibrous sheath. Plays a role in sperm motility. {ECO:0000269PubMed:9822690}.

Subcellular Localization

Cell projection, cilium, flagellum {ECO:0000269PubMed:9822690}. Note=Localizes to the principle piece of the sperm flagellum.

Disease Associations

Tissue Specificity

Testis specific; only expressed in round spermatids. {ECO:0000269PubMed:9514854}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0051018	protein kinase A binding

Biological Process

GO:0006928	cellular component movement
GO:0007165	signal transduction
GO:0007338	single fertilization
GO:0030030	cell projection organization
GO:0030317	sperm motility