InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HIST1H1T

Summary

InnateDB Protein

IDBP-67835.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HIST1H1T

Protein Name

histone cluster 1, H1t

Synonyms

dJ221C16.2; H1FT; H1t;

Species

Homo sapiens

Ensembl Protein

ENSP00000341214

InnateDB Gene

IDBG-67833 (HIST1H1T)

Protein Structure

UniProt Annotation

Function

Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.

Subcellular Localization

Nucleus. Chromosome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding

Biological Process

GO:0006334	nucleosome assembly
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0007339	binding of sperm to zona pellucida
GO:0030154	cell differentiation
GO:0030317	sperm motility

Cellular Component

GO:0000786	nucleosome
GO:0000794	condensed nuclear chromosome
GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR005818 Linker histone H1/H5, domain H15
IPR005819 Histone H5

PFAM

PF00538

PRINTS

PR00624

PIRSF

SMART

SM00526

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P22492

PhosphoSite

PhosphoSite-P22492

TrEMBL

UniProt Splice Variant

Entrez Gene

3010

UniGene

Hs.533293

RefSeq

NP_005314

HUGO

HGNC:4720

OMIM

142712

CCDS

CCDS34349

HPRD

00822

IMGT

EMBL

AF531301 BC069517 M60094 M97755

GenPept

AAA19936 AAA35944 AAH69517 AAN06701