InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TBCE

Summary

InnateDB Protein

IDBP-679851.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TBCE

Protein Name

Tubulin-specific chaperone E

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018249

InnateDB Gene

IDBG-628488 (TBCE)

Protein Structure

UniProt Annotation

Function

Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0007023	post-chaperonin tubulin folding pathway
GO:0007409	axonogenesis
GO:0008344	adult locomotory behavior
GO:0009791	post-embryonic development
GO:0014889	muscle atrophy
GO:0048589	developmental growth
GO:0048936	peripheral nervous system neuron axonogenesis

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000626 Ubiquitin-like
IPR000938 CAP Gly-rich domain
IPR029071 Ubiquitin-related domain

PFAM

PF00240
PF14560
PF01302

PRINTS

PIRSF

SMART

SM00213
SM01052

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q32KS0

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

505066

UniGene

Bt.3254

RefSeq

NP_001033121

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC109955 BT026156

GenPept

AAI09956 ABG66995