InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TBCE

Summary

InnateDB Gene

IDBG-628488.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TBCE

Gene Name

Tubulin-specific chaperone E

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013735

Encoded Proteins

IDBP-679851

Tubulin-specific chaperone E

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116957:
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 28:8143951-8232969

Strand

Forward strand

Band

Transcripts

ENSBTAT00000018249

ENSBTAP00000018249

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0007023	post-chaperonin tubulin folding pathway
GO:0007409	axonogenesis
GO:0008344	adult locomotory behavior
GO:0009791	post-embryonic development
GO:0014889	muscle atrophy
GO:0048589	developmental growth
GO:0048936	peripheral nervous system neuron axonogenesis