Version 5.4
| Bos taurus Protein: GFM2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-679889.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GFM2 | ||||||||
| Protein Name | Ribosome-releasing factor 2, mitochondrial | ||||||||
| Synonyms | EF-G2mt; mEF-G 2; RRF2mt; | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000048999 | ||||||||
| InnateDB Gene | IDBG-628523 (GFM2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. {ECO:0000255HAMAP-Rule:MF_03059}. | ||||||||
| Subcellular Localization | Mitochondrion {ECO:0000255HAMAP- Rule:MF_03059}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000640
Translation elongation factor EFG, V domain IPR000795 Elongation factor, GTP-binding domain IPR004161 Translation elongation factor EFTu/EF1A, domain 2 IPR005225 Small GTP-binding protein domain IPR005517 Translation elongation factor EFG/EF2, domain IV IPR009000 Translation protein, beta-barrel domain IPR009022 Elongation factor G, III-V domain IPR020568 Ribosomal protein S5 domain 2-type fold IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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| PFAM |
PF00679
PF00009 PF03144 PF03764 PF14492 |
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| PRINTS |
PR00315
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| PIRSF | |||||||||
| SMART |
SM00838
SM00889 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A6QNM2 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 527467 | ||||||||
| UniGene | Bt.62475 | ||||||||
| RefSeq | NP_001095579 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC148895 | ||||||||
| GenPept | AAI48896 | ||||||||