Version 5.4
| Bos taurus Gene: GFM2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-628523.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GFM2 | ||||||||
| Gene Name | Ribosome-releasing factor 2, mitochondrial | ||||||||
| Synonyms | EF-G2mt; mEF-G 2; RRF2mt | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000015519 | ||||||||
| Encoded Proteins |
Ribosome-releasing factor 2, mitochondrial
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164347:
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 20:6669168-6721360 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Mitochondrial translation pathway
Mitochondrial translation termination pathway
Organelle biogenesis and maintenance pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation termination pathway
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation termination pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | A6QNM2 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 527467 | ||||||||
| UniGene | Bt.62034 Bt.62475 | ||||||||
| RefSeq | NM_001102109 XM_003583674 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC148895 | ||||||||
| GenPept | AAI48896 | ||||||||
| RNA Seq Atlas | 100850514 527467 | ||||||||