InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NFASC

Summary

InnateDB Protein

IDBP-680090.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NFASC

Protein Name

neurofascin

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000054775

InnateDB Gene

IDBG-628670 (NFASC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0086080	protein binding involved in heterotypic cell-cell adhesion

Biological Process

GO:0002175	protein localization to paranode region of axon
GO:0007411	axon guidance
GO:0007422	peripheral nervous system development
GO:0019226	transmission of nerve impulse
GO:0030913	paranodal junction assembly
GO:0034113	heterotypic cell-cell adhesion
GO:0042552	myelination
GO:0045162	clustering of voltage-gated sodium channels
GO:0050808	synapse organization
GO:0071205	protein localization to juxtaparanode region of axon

Cellular Component

GO:0005886	plasma membrane
GO:0030424	axon
GO:0033010	paranodal junction
GO:0033270	paranode region of axon
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite