Version 5.4
Bos taurus Protein: BT.24236
Summary
InnateDB Protein IDBP-680107.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.24236
Protein Name deleted in liver cancer 1
Synonyms DLC-1; StARD12;
Species Bos taurus
Ensembl Protein ENSBTAP00000020664
InnateDB Gene IDBG-628726 (BT.24236)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0042169 SH2 domain binding
Biological Process
GO:0001843 neural tube closure
GO:0003007 heart morphogenesis
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 signal transduction
GO:0008285 negative regulation of cell proliferation
GO:0008360 regulation of cell shape
GO:0021575 hindbrain morphogenesis
GO:0030036 actin cytoskeleton organization
GO:0030336 negative regulation of cell migration
GO:0030900 forebrain development
GO:0032321 positive regulation of Rho GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0035023 regulation of Rho protein signal transduction
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035307 positive regulation of protein dephosphorylation
GO:0048041 focal adhesion assembly
GO:0051497 negative regulation of stress fiber assembly
GO:1900119 positive regulation of execution phase of apoptosis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005901 caveola
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR002913 START domain
IPR008936 Rho GTPase activation protein
IPR011510 Sterile alpha motif, type 2
PFAM PF00620
PF01852
PF07647
PRINTS
PIRSF
SMART SM00324
SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MIZ8
UniProt Splice Variant
Entrez Gene 511433
UniGene Bt.24236
RefSeq NP_001095963
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02060353 DAAA02060354 DAAA02060355
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca