InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TAP1

Summary

InnateDB Protein

IDBP-680237.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAP1

Protein Name

antigen peptide transporter 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045934

InnateDB Gene

IDBG-628856 (TAP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0015197	peptide transporter activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0023029	MHC class Ib protein binding
GO:0042288	MHC class I protein binding
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0043531	ADP binding
GO:0046979	TAP2 binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0006952	defense response
GO:0008152	metabolic process
GO:0015833	peptide transport
GO:0019060	intracellular transport of viral protein in host cell
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0046967	cytosol to ER transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030176	integral component of endoplasmic reticulum membrane
GO:0042825	TAP complex

Protein Structure and Domains

PDB ID

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR005293 Antigen peptide transporter 2
IPR011527 ABC transporter type 1, transmembrane domain
IPR013305 ABC transporter, ABCB2
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005

PRINTS

PR01896

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A6QPZ6

UniProt Splice Variant

Entrez Gene

524959

UniGene

Bt.58251

RefSeq

NP_001091527

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC149569 DAAA02054878

GenPept

AAI49570