InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ISG20

Summary

InnateDB Protein

IDBP-680294.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ISG20

Protein Name

interferon stimulated exonuclease gene 20kDa

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000056176

InnateDB Gene

IDBG-628915 (ISG20)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000175	3'-5'-exoribonuclease activity
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0030619	U1 snRNA binding
GO:0030620	U2 snRNA binding
GO:0034511	U3 snoRNA binding

Biological Process

GO:0000738	DNA catabolic process, exonucleolytic
GO:0006401	RNA catabolic process
GO:0009615	response to virus
GO:0045071	negative regulation of viral genome replication
GO:0051607	defense response to virus

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0015030	Cajal body
GO:0016605	PML body

Protein Structure and Domains

PDB ID

InterPro

IPR006055 Exonuclease
IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III

PFAM

PF00929

PRINTS

PIRSF

SMART

SM00479

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3N2Q8

UniProt Splice Variant

Entrez Gene

506604

UniGene

Bt.22275

RefSeq

HUGO

HGNC:6130

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02052106

GenPept