InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PDE4D

Summary

InnateDB Protein

IDBP-680296.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDE4D

Protein Name

phosphodiesterase 4D, cAMP-specific

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000631

InnateDB Gene

IDBG-628921 (PDE4D)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity
GO:0005515	protein binding
GO:0008081	phosphoric diester hydrolase activity
GO:0008144	drug binding
GO:0016787	hydrolase activity
GO:0030552	cAMP binding
GO:0031625	ubiquitin protein ligase binding
GO:0046872	metal ion binding
GO:0051117	ATPase binding
GO:0097110	scaffold protein binding

Biological Process

GO:0006198	cAMP catabolic process
GO:0006939	smooth muscle contraction
GO:0007165	signal transduction
GO:0007568	aging
GO:0008152	metabolic process
GO:0030593	neutrophil chemotaxis
GO:0032729	positive regulation of interferon-gamma production
GO:0032743	positive regulation of interleukin-2 production
GO:0032754	positive regulation of interleukin-5 production
GO:0035264	multicellular organism growth
GO:0050852	T cell receptor signaling pathway
GO:0050900	leukocyte migration
GO:0071222	cellular response to lipopolysaccharide
GO:0071320	cellular response to cAMP
GO:0071872	cellular response to epinephrine stimulus