Version 5.4
| Bos taurus Protein: TFPI2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-680465.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | TFPI2 | ||||||||
| Protein Name | Tissue factor pathway inhibitor 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000021062 | ||||||||
| InnateDB Gene | IDBG-629080 (TFPI2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. {ECO:0000269PubMed:12921785}. | ||||||||
| Subcellular Localization | Secreted {ECO:0000269PubMed:12921785}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR002223
Proteinase inhibitor I2, Kunitz metazoa IPR008296 Proteinase inhibitor I2, tissue factor pathway inhibitor |
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| PFAM |
PF00014
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| PRINTS |
PR00759
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| PIRSF |
PIRSF001620
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| SMART |
SM00131
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q7YRQ8 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 360007 | ||||||||
| UniGene | Bt.69449 | ||||||||
| RefSeq | NP_877589 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AY234861 BC103205 | ||||||||
| GenPept | AAI03206 AAO84035 | ||||||||