Bos taurus Gene: TFPI2
Summary
InnateDB Gene IDBG-629080.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFPI2
Gene Name Tissue factor pathway inhibitor 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015844
Encoded Proteins
Tissue factor pathway inhibitor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105825:
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:11035479-11039782
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021062 ENSBTAP00000021062
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0007596 blood coagulation
GO:0007599 hemostasis
GO:0010466 negative regulation of peptidase activity
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q7YRQ8
TrEMBL
UniProt Splice Variant
Entrez Gene 360007
UniGene Bt.29514 Bt.69449
RefSeq NM_182788
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY234861 BC103205
GenPept AAI03206 AAO84035
RNA Seq Atlas 360007