Version 5.4
Bos taurus Protein: PON1
Summary
InnateDB Protein IDBP-680696.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PON1
Protein Name serum paraoxonase/arylesterase 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020790
InnateDB Gene IDBG-629289 (PON1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004063 aryldialkylphosphatase activity
GO:0004064 arylesterase activity
GO:0005509 calcium ion binding
GO:0005543 phospholipid binding
GO:0016844 strictosidine synthase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0009058 biosynthetic process
GO:0009636 response to toxic substance
GO:0010875 positive regulation of cholesterol efflux
GO:0019439 aromatic compound catabolic process
GO:0032411 positive regulation of transporter activity
GO:0046395 carboxylic acid catabolic process
GO:0046434 organophosphate catabolic process
GO:0046470 phosphatidylcholine metabolic process
GO:0051099 positive regulation of binding
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0034366 spherical high-density lipoprotein particle
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR002640 Arylesterase
IPR008363 Paraoxonase1
IPR013658 SMP-30/Gluconolactonase/LRE-like region
IPR018119 Strictosidine synthase, conserved region
PFAM PF01731
PF08450
PF03088
PRINTS PR01785
PR01786
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2KIW1
UniProt Splice Variant
Entrez Gene 523798
UniGene Bt.19690
RefSeq NP_001039734
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112488 DAAA02009788
GenPept AAI12489

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca