Version 5.4
Bos taurus Protein: HHIP
Summary
InnateDB Protein IDBP-680906.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HHIP
Protein Name hedgehog-interacting protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021390
InnateDB Gene IDBG-629493 (HHIP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
GO:0048038 quinone binding
GO:0097108 hedgehog family protein binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007165 signal transduction
GO:0007224 smoothened signaling pathway
GO:0007405 neuroblast proliferation
GO:0009887 organ morphogenesis
GO:0009953 dorsal/ventral pattern formation
GO:0009968 negative regulation of signal transduction
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
GO:0045879 negative regulation of smoothened signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0055114 oxidation-reduction process
GO:0060441 epithelial tube branching involved in lung morphogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase
IPR018143 Folate receptor-like
PFAM PF00008
PF03024
PRINTS
PIRSF
SMART SM00181
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A5PJW9
UniProt Splice Variant
Entrez Gene 540830
UniGene Bt.88165
RefSeq NP_001092584
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142268 BC142422 DAAA02044345 DAAA02044346 DAAA02044347
GenPept AAI42269 AAI42423

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca