InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MB21D1

Summary

InnateDB Protein

IDBP-680968.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MB21D1

Protein Name

Mab-21 domain containing 1

Synonyms

cGAS;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001184

InnateDB Gene

IDBG-629558 (MB21D1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0016740	transferase activity
GO:0016779	nucleotidyltransferase activity
GO:0046872	metal ion binding
GO:0061501	cyclic-GMP-AMP synthase activity

Biological Process

GO:0002218	activation of innate immune response
GO:0002230	positive regulation of defense response to virus by host
GO:0002376	immune system process
GO:0009190	cyclic nucleotide biosynthetic process
GO:0045087	innate immune response
GO:0051607	defense response to virus
GO:0071360	cellular response to exogenous dsRNA

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR024810 Mab-21 domain

PFAM

PF03281

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

E1BGN7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

782472

UniGene

RefSeq

XP_001251099

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02025231

GenPept