Version 5.4
Bos taurus Protein: PPA1
Summary
InnateDB Protein IDBP-681077.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPA1
Protein Name Inorganic pyrophosphatase
Synonyms PP;
Species Bos taurus
Ensembl Protein ENSBTAP00000010311
InnateDB Gene IDBG-629658 (PPA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Highest levels are found in retinal rod outer segments.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphatase activity
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006796 phosphate-containing compound metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008162 Inorganic pyrophosphatase
PFAM PF00719
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P37980
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280701
UniGene
RefSeq NP_001068586
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114891 M95283
GenPept AAI14892

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca