Version 5.4
Bos taurus Gene: PPA1
Summary
InnateDB Gene IDBG-629658.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPA1
Gene Name Inorganic pyrophosphatase
Synonyms PP
Species Bos taurus
Ensembl Gene ENSBTAG00000007836
Encoded Proteins
IDBP-681077
Inorganic pyrophosphatase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000180817:
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 28:26576202-26614511
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010311 ENSBTAP00000010311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphatase activity
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006796 phosphate-containing compound metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000180817
View Gene Order
ENSMUSG00000020089
View Gene Order
Pathways
NETPATH
REACTOME
REACT_218260
tRNA Aminoacylation pathway
REACT_226022
Gene Expression pathway
REACT_209045
Cytosolic tRNA aminoacylation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15306
Cytosolic tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
REACT_255897
Cytosolic tRNA aminoacylation pathway
REACT_233803
tRNA Aminoacylation pathway
REACT_233572
Gene Expression pathway
KEGG
hsa00190
Oxidative phosphorylation pathway
mmu00190
Oxidative phosphorylation pathway
INOH
PID NCI
Cross-References
SwissProt P37980
TrEMBL
UniProt Splice Variant
Entrez Gene 280701
UniGene
RefSeq NM_001075118
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114891 M95283
GenPept AAI14892
RNA Seq Atlas 280701

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca