InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PBX1

Summary

InnateDB Protein

IDBP-681188.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PBX1

Protein Name

pre-B-cell leukemia homeobox 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018349

InnateDB Gene

IDBG-629771 (PBX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.

Predicted by orthology
Total	45 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001655	urogenital system development
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0006355	regulation of transcription, DNA-templated
GO:0008284	positive regulation of cell proliferation
GO:0009887	organ morphogenesis
GO:0009952	anterior/posterior pattern specification
GO:0009954	proximal/distal pattern formation
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
GO:0030278	regulation of ossification
GO:0030325	adrenal gland development
GO:0030326	embryonic limb morphogenesis
GO:0035162	embryonic hemopoiesis
GO:0042127	regulation of cell proliferation
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045665	negative regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048536	spleen development
GO:0048538	thymus development
GO:0048568	embryonic organ development
GO:0048706	embryonic skeletal system development