Bos taurus Protein: SPG20
Summary
InnateDB Protein IDBP-681369.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPG20
Protein Name Spartin
Synonyms spartin;
Species Bos taurus
Ensembl Protein ENSBTAP00000010577
InnateDB Gene IDBG-629941 (SPG20)
Protein Structure
UniProt Annotation
Function May be implicated in endosomal trafficking, or microtubule dynamics, or both. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Note=Transiently associated with endosomes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0009838 abscission
GO:0030514 negative regulation of BMP signaling pathway
GO:0034389 lipid particle organization
GO:0048698 negative regulation of collateral sprouting in absence of injury
GO:0050905 neuromuscular process
GO:0051301 cell division
GO:0051881 regulation of mitochondrial membrane potential
GO:0060612 adipose tissue development
Cellular Component
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005811 lipid particle
GO:0005886 plasma membrane
GO:0030496 midbody
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR007330 MIT
IPR009686 Senescence/spartin-associated
PFAM PF04212
PF06911
PRINTS
PIRSF
SMART SM00745
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A0JNJ3
PhosphoSite PhosphoSite-
TrEMBL F2Y8L9
UniProt Splice Variant
Entrez Gene 534027
UniGene Bt.21619
RefSeq NP_001071464
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126710 HQ826870
GenPept AAI26711 ADZ53823