Version 5.4
Bos taurus Protein: BT.45725
Summary
InnateDB Protein IDBP-681476.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.45725
Protein Name cyclin-dependent kinase 4 inhibitor B
Synonyms MTS2;
Species Bos taurus
Ensembl Protein ENSBTAP00000002652
InnateDB Gene IDBG-630040 (BT.45725)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000086 G2/M transition of mitotic cell cycle
GO:0007050 cell cycle arrest
GO:0007093 mitotic cell cycle checkpoint
GO:0008285 negative regulation of cell proliferation
GO:0030219 megakaryocyte differentiation
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031668 cellular response to extracellular stimulus
GO:0031670 cellular response to nutrient
GO:0042326 negative regulation of phosphorylation
GO:0048536 spleen development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N340
UniProt Splice Variant
Entrez Gene 527124
UniGene Bt.45725
RefSeq NP_001069362
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02022236
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca