InnateDB Protein
|
IDBP-681538.2
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
FDX1
|
Protein Name
|
Adrenodoxin, mitochondrial
|
Synonyms
|
|
Species
|
Bos taurus
|
Ensembl Protein
|
ENSBTAP00000015660
|
InnateDB Gene
|
IDBG-630095 (FDX1)
|
Protein Structure
|
|
Function |
Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Mitochondrion matrix.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
4 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001041
2Fe-2S ferredoxin-type domain
IPR001055
Adrenodoxin
|
PFAM |
PF00111
|
PRINTS |
PR00355
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P00257
|
PhosphoSite |
PhosphoSite-P00257
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
281157
|
UniGene |
Bt.1573
|
RefSeq |
|
HUGO |
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
BC109849
BT030601
D00467
D00471
M11746
M16934
M19474
M19656
S78831
|
GenPept |
AAA30357
AAA30358
AAA78950
AAB21264
AAI09850
ABQ13041
BAA00362
BAA00363
|
|
|