InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: FDX1

Summary

InnateDB Gene

IDBG-630095.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FDX1

Gene Name

Adrenodoxin, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011793

Encoded Proteins

IDBP-681535

Adrenodoxin, mitochondrial

IDBP-681538

Adrenodoxin, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137714:
This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:20772023-20807753

Strand

Forward strand

Band

Transcripts

ENSBTAT00000033850	ENSBTAP00000033758
ENSBTAT00000015660	ENSBTAP00000015660

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0009055	electron carrier activity
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051537	2 iron, 2 sulfur cluster binding

Biological Process

GO:0006629	lipid metabolic process
GO:0006694	steroid biosynthetic process
GO:0008202	steroid metabolic process
GO:0008203	cholesterol metabolic process
GO:0042446	hormone biosynthetic process
GO:0055114	oxidation-reduction process