Version 5.4
Bos taurus Protein: NPAS2
Summary
InnateDB Protein IDBP-681946.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPAS2
Protein Name neuronal PAS domain-containing protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026257
InnateDB Gene IDBG-630469 (NPAS2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
GO:0051879 Hsp90 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0042745 circadian sleep/wake cycle
GO:0045475 locomotor rhythm
GO:0045739 positive regulation of DNA repair
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051775 response to redox state
GO:0060548 negative regulation of cell death
GO:2001020 regulation of response to DNA damage stimulus
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000014 PAS domain
IPR001067 Nuclear translocator
IPR001610 PAC motif
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR013655 PAS fold-3
IPR013767 PAS fold
PFAM PF13188
PF13426
PF00010
PF08447
PF00989
PRINTS PR00785
PIRSF
SMART SM00091
SM00086
SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6QL92
UniProt Splice Variant
Entrez Gene 614049
UniGene Bt.55456
RefSeq NP_001077232
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134580 DAAA02030201
GenPept AAI34581

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca