InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GLRB

Summary

InnateDB Protein

IDBP-682090.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GLRB

Protein Name

glycine receptor subunit beta precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000029010

InnateDB Gene

IDBG-630612 (GLRB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005488	binding
GO:0005515	protein binding
GO:0016594	glycine binding
GO:0016933	extracellular-glycine-gated ion channel activity
GO:0016934	extracellular-glycine-gated chloride channel activity

Biological Process

GO:0001964	startle response
GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0007218	neuropeptide signaling pathway
GO:0007268	synaptic transmission
GO:0007340	acrosome reaction
GO:0007399	nervous system development
GO:0007601	visual perception
GO:0007628	adult walking behavior
GO:0034220	ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0050905	neuromuscular process
GO:0060012	synaptic transmission, glycinergic
GO:0060013	righting reflex
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
IPR008060 Glycine receptor beta

PFAM

PF02932
PF02931

PRINTS

PR00253
PR00252
PR01677

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite