Version 5.4
Bos taurus Protein: POMP
Summary
InnateDB Protein IDBP-682104.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POMP
Protein Name Proteasome maturation protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018626
InnateDB Gene IDBG-630638 (POMP)
Protein Structure
UniProt Annotation
Function Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation (By similarity). Mediates the association of 20S preproteasome with the endoplasmic reticulum (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Microsome membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043248 proteasome assembly
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0016020 membrane
GO:0031090 organelle membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR008012 Proteasome maturation factor UMP1
PFAM PF05348
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SZV5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510314
UniGene Bt.48903
RefSeq NP_001029548
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102689
GenPept AAI02690

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca