Version 5.4
Bos taurus Gene: POMP
Summary
InnateDB Gene IDBG-630638.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POMP
Gene Name Proteasome maturation protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014024
Encoded Proteins
IDBP-682104
Proteasome maturation protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132963:
The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.[provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:31492830-31503972
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018626 ENSBTAP00000018626
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043248 proteasome assembly
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0016020 membrane
GO:0031090 organelle membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132963
View Gene Order
ENSMUSG00000029649
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03050
Proteasome pathway
mmu03050
Proteasome pathway
INOH
PID NCI
Cross-References
SwissProt Q3SZV5
TrEMBL
UniProt Splice Variant
Entrez Gene 510314
UniGene Bt.48903
RefSeq NM_001034376
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102689
GenPept AAI02690
RNA Seq Atlas 510314

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca