InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ABCB1

Summary

InnateDB Protein

IDBP-682128.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCB1

Protein Name

ATP-binding cassette transporter subfamily B member 1

Synonyms

MDR1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020806

InnateDB Gene

IDBG-630429 (ABCB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0008152	metabolic process
GO:0055085	transmembrane transport
GO:0072089	stem cell proliferation

Cellular Component

GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR019195 ABC transporter, ATPase, putative
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005
PF09818

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite