InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GUCY1B1

Summary

InnateDB Protein

IDBP-682143.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GUCY1B1

Protein Name

Guanylate cyclase soluble subunit beta-1

Synonyms

GUCY1B1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005009

InnateDB Gene

IDBG-630664 (GUCY1B1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Lung and brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004383	guanylate cyclase activity
GO:0005525	GTP binding
GO:0016829	lyase activity
GO:0016849	phosphorus-oxygen lyase activity
GO:0020037	heme binding
GO:0046872	metal ion binding

Biological Process

GO:0006182	cGMP biosynthetic process
GO:0006810	transport
GO:0006811	ion transport
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction
GO:0055072	iron ion homeostasis

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
IPR011644 Heme-NO binding
IPR011645 Haem NO binding associated
IPR024096 NO signalling/Golgi transport ligand-binding domain
IPR029787 Nucleotide cyclase

PFAM

PF00211
PF07700
PF07701

PRINTS

PIRSF

SMART

SM00044

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P16068