InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: APCS

Summary

InnateDB Protein

IDBP-682232.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APCS

Protein Name

Serum amyloid P-component

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026133

InnateDB Gene

IDBG-630753 (APCS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001849	complement component C1q binding
GO:0005509	calcium ion binding
GO:0046790	virion binding
GO:0046872	metal ion binding

Biological Process

GO:0045087	innate immune response
GO:0045656	negative regulation of monocyte differentiation
GO:0046597	negative regulation of viral entry into host cell
GO:0048525	negative regulation of viral process
GO:1903016	negative regulation of exo-alpha-sialidase activity
GO:1903019	negative regulation of glycoprotein metabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR001759 Pentaxin
IPR008985 Concanavalin A-like lectin/glucanases superfamily

PFAM

PF00354

PRINTS

PR00895

PIRSF

SMART

SM00159

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3T004

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

514488

UniGene

Bt.17678

RefSeq

NP_001029638

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102623

GenPept

AAI02624