Version 5.4
Bos taurus Protein: TYRP1
Summary
InnateDB Protein IDBP-682334.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TYRP1
Protein Name 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027945
InnateDB Gene IDBG-630848 (TYRP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006582 melanin metabolic process
GO:0008152 metabolic process
GO:0030318 melanocyte differentiation
GO:0032438 melanosome organization
GO:0042438 melanin biosynthetic process
GO:0043438 acetoacetic acid metabolic process
GO:0043473 pigmentation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0010008 endosome membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0033162 melanosome membrane
GO:0042470 melanosome
Protein Structure and Domains
PDB ID
InterPro IPR002227 Tyrosinase copper-binding domain
IPR008922 Uncharacterised domain, di-copper centre
PFAM PF00264
PRINTS PR00092
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q95MD7
UniProt Splice Variant
Entrez Gene 282105
UniGene Bt.221
RefSeq NP_776905
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF398512 DAAA02022458 DAAA02022459 GQ179991
GenPept AAK94986 ACS66870

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca