InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TREM2

Summary

InnateDB Protein

IDBP-682346.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TREM2

Protein Name

triggering receptor expressed on myeloid cells 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009568

InnateDB Gene

IDBG-630863 (TREM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001530	lipopolysaccharide binding
GO:0005515	protein binding
GO:0097110	scaffold protein binding

Biological Process

GO:0002588	positive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850	positive regulation of calcium-mediated signaling
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0097028	dendritic cell differentiation
GO:1903078	positive regulation of protein localization to plasma membrane
GO:1903082	positive regulation of C-C chemokine receptor CCR7 signaling pathway
GO:2000350	positive regulation of CD40 signaling pathway

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain

PFAM

PF07686

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q05B59

UniProt Splice Variant

Entrez Gene

506467

UniGene

Bt.45563

RefSeq

NP_001073048

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC122771 DAAA02055058

GenPept

AAI22772