InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: IL18R1

Summary

InnateDB Protein

IDBP-682357.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IL18R1

Protein Name

interleukin 18 receptor 1

Synonyms

IL-18Ra;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001371

InnateDB Gene

IDBG-630853 (IL18R1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004908	interleukin-1 receptor activity
GO:0005515	protein binding
GO:0042008	interleukin-18 receptor activity

Biological Process

GO:0007165	signal transduction
GO:0030101	natural killer cell activation
GO:0032729	positive regulation of interferon-gamma production
GO:0035655	interleukin-18-mediated signaling pathway
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0045063	T-helper 1 cell differentiation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR007110 Immunoglobulin-like domain

PFAM

PF01582
PF13676

PRINTS

PR01536

PIRSF

SMART

SM00255
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt