InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GRM3

Summary

InnateDB Protein

IDBP-682364.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GRM3

Protein Name

metabotropic glutamate receptor 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025275

InnateDB Gene

IDBG-630880 (GRM3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001641	group II metabotropic glutamate receptor activity
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0005246	calcium channel regulator activity

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0051966	regulation of synaptic transmission, glutamatergic

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon
GO:0042734	presynaptic membrane
GO:0043005	neuron projection
GO:0043197	dendritic spine
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000162 GPCR, family 3, metabotropic glutamate receptor
IPR000337 GPCR, family 3
IPR001234 GPCR, family 3, metabotropic glutamate receptor 3
IPR001458 GPCR, family 3, metabotropic glutamate receptor 2
IPR001828 Extracellular ligand-binding receptor
IPR011500 GPCR, family 3, nine cysteines domain
IPR017978 GPCR, family 3, C-terminal
IPR028082 Periplasmic binding protein-like I

PFAM

PF01094
PF07562
PF00003

PRINTS

PR00593
PR00248
PR01053
PR01052

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite