InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.65618

Summary

InnateDB Protein

IDBP-682518.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.65618

Protein Name

DNA polymerase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009882

InnateDB Gene

IDBG-630895 (BT.65618)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0008270	zinc ion binding
GO:0016740	transferase activity
GO:0016779	nucleotidyltransferase activity

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0000731	DNA synthesis involved in DNA repair
GO:0006139	nucleobase-containing compound metabolic process
GO:0006260	DNA replication
GO:0006261	DNA-dependent DNA replication
GO:0006287	base-excision repair, gap-filling
GO:0006297	nucleotide-excision repair, DNA gap filling

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0008622	epsilon DNA polymerase complex

Protein Structure and Domains

PDB ID

InterPro

IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain
IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain
IPR006172 DNA-directed DNA polymerase, family B
IPR012337 Ribonuclease H-like domain
IPR013697 DNA polymerase epsilon, catalytic subunit A, C-terminal
IPR019288 Predicted 3\'-5\' exonuclease, PolB-like

PFAM

PF03104
PF00136
PF08490
PF10108

PRINTS

PR00106

PIRSF

SMART

SM00486

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt