Version 5.4
Bos taurus Protein: PDE1B
Summary
InnateDB Protein IDBP-682565.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDE1B
Protein Name Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005680
InnateDB Gene IDBG-631069 (PDE1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0001505 regulation of neurotransmitter levels
GO:0001975 response to amphetamine
GO:0006198 cAMP catabolic process
GO:0007165 signal transduction
GO:0007626 locomotory behavior
GO:0008542 visual learning
GO:0030224 monocyte differentiation
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus
GO:0042053 regulation of dopamine metabolic process
GO:0042428 serotonin metabolic process
GO:0046069 cGMP catabolic process
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002073 3\'5\'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003607 HD/PDEase domain
IPR013706 3\'5\'-cyclic nucleotide phosphodiesterase N-terminal
IPR023088 3\'5\'-cyclic nucleotide phosphodiesterase
PFAM PF00233
PF08499
PRINTS PR00387
PIRSF
SMART SM00471
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0VCW5
UniProt Splice Variant
Entrez Gene 281970
UniGene Bt.3910
RefSeq XP_005206149
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119963 BC154399 DAAA02012826
GenPept AAI19964 AAI54400

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca