Version 5.4
Bos taurus Protein: IREB2
Summary
InnateDB Protein IDBP-682574.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IREB2
Protein Name iron-responsive element binding protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003252
InnateDB Gene IDBG-631031 (IREB2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030350 iron-responsive element binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006417 regulation of translation
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006879 cellular iron ion homeostasis
GO:0008152 metabolic process
GO:0009791 post-embryonic development
GO:0010468 regulation of gene expression
GO:0030316 osteoclast differentiation
GO:0034101 erythrocyte homeostasis
GO:0050892 intestinal absorption
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel
IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha
IPR006249 Aconitate/iron regulatory protein 2
IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel
PFAM PF00694
PF00330
PRINTS PR00415
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BNR2
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:6115
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02052431 DAAA02052432 DAAA02052433
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca