Version 5.4
Bos taurus Protein: SUZ12
Summary
InnateDB Protein IDBP-682764.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUZ12
Protein Name suppressor of zeste 12 homolog (Drosophila)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024971
InnateDB Gene IDBG-631171 (SUZ12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 77 interaction(s) predicted by orthology.
Predicted by orthology
Total 77 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0035064 methylated histone binding
GO:0042054 histone methyltransferase activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0008284 positive regulation of cell proliferation
GO:0016571 histone methylation
GO:0016574 histone ubiquitination
GO:0045596 negative regulation of cell differentiation
Cellular Component
GO:0001739 sex chromatin
GO:0005634 nucleus
GO:0035098 ESC/E(Z) complex
Protein Structure and Domains
PDB ID
InterPro IPR019135 Polycomb protein, VEFS-Box
PFAM PF09733
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1B9T7
UniProt Splice Variant
Entrez Gene 538774
UniGene Bt.14133
RefSeq NP_001192516
HUGO HGNC:17101
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048525
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca