Version 5.4
Bos taurus Protein: BT.37798
Summary
InnateDB Protein IDBP-683033.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.37798
Protein Name seven in absentia homolog 1 (Drosophila)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000052492
InnateDB Gene IDBG-631496 (BT.37798)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 80 interaction(s) predicted by orthology.
Predicted by orthology
Total 80 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007275 multicellular organismal development
GO:0016567 protein ubiquitination
GO:0030163 protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0030877 beta-catenin destruction complex
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR008974 TRAF-like
IPR013010 Zinc finger, SIAH-type
IPR018121 Seven-in-absentia protein, TRAF-like domain
PFAM PF13639
PF14634
PF03145
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N5G3
UniProt Splice Variant
Entrez Gene 534655
UniGene Bt.37798
RefSeq NP_001180122
HUGO HGNC:10857
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046333
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca