Version 5.4
Bos taurus Protein: VTN
Summary
InnateDB Protein IDBP-683124.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VTN
Protein Name vitronectin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021497
InnateDB Gene IDBG-631579 (VTN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 69 interaction(s) predicted by orthology.
Predicted by orthology
Total 69 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0030247 polysaccharide binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
GO:0007160 cell-matrix adhesion
GO:0010811 positive regulation of cell-substrate adhesion
GO:0010951 negative regulation of endopeptidase activity
GO:0014911 positive regulation of smooth muscle cell migration
GO:0030198 extracellular matrix organization
GO:0032092 positive regulation of protein binding
GO:0033627 cell adhesion mediated by integrin
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0061302 smooth muscle cell-matrix adhesion
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR000585 Hemopexin-like domain
IPR001212 Somatomedin B domain
IPR018487 Hemopexin-like repeats
IPR020436 Somatomedin B, chordata
PFAM PF01033
PF00045
PRINTS PR00022
PIRSF
SMART SM00201
SM00120
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3ZBS7
UniProt Splice Variant
Entrez Gene 507525
UniGene Bt.49491
RefSeq NP_001030222
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103132 DAAA02048600
GenPept AAI03133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca